Hemangiosarcoma
Hemangiosarcoma is a malignant tumor of blood vessel cells. This tumor
is associated with serious internal bleeding and involves rapid internal
spread.
It can
come from any tissue where there are blood vessels, however, there are
three classical locations :
- Skin and Subcutaneous forms
- Splenic forms
- Heart Base forms
The Skin Form
They are
the most easily removed surgically. They are classified as either “dermal” and “subcutaneous” (also called Hypodermal). The true skin
form looks like a rosy red or even black growth on the skin. It is
associated with sun exposure and tends to form on non-hair or sparsely
haired skin like on the abdomen, or on areas with white fur. Dogs with
short white haired fur such as Dalmations, pit bull terriers and Albino
Dobermans are predisposed to this tumor. 1/3 of cases will spread
internally malignantly.
* A biopsy
will indicate whether or not the growth was “completely exiced” (cut
out).
To be
absolutely positive there has been no spread following surgery, the
following tests are necessary.
-
Chest
x-rays - Hemangiosarcoma tends to spread to the lungs. Any spots must
be 3cm in diameter to be large enough to be
visible by x-ray
-
Ultrasound of the belly - specifically the spleen. Even a small tumor will be
visible
-
Ultrasound of the heart - a small tumor should be easily visible by
ultrasound
The Subcutaneous or Hypodermal Form
The
overlying skin is often totally normal to the naked eye on top of a
subcutaneous hemangiosarcoma. Often the surgeon is surprised to find a
dark red blood growth under the skin once the tumor has been removed.
Up to 60%
of these tumors spread internally and the above test are even more
important to ensure the tumor has been removed. If no sign of the tumor
spreading is found after chest ultrasound or heart ultrasound, and the
belly is clear, prognosis is much better. Additional treatment with
chemotherapy may be recommended if cure is the goal. 6 months or 172
days is the median survival time with surgery alone.
Hemangiosarcoma of the Spleen
The
spleen is a fairly deep-seated abdominal organ which tends to go
undetected unless it develops a growth of significant size. Splenic
growths have the unfortunate tendancy to break or burst open and bleed
profusely regardless whether they are benign or malignant because of the
blood supply to that organ. Splenic hemangiosarcoma is a rapidly
spreading malignancy and removal of the spleen will reduce the
life-threatening prospect of a sudden bleed. 25% of dogs with splenic
hemangiosarcoma also have a heart-based hemangiosarcoma. Survival time
even with surgery is approximately 19 - 65 days.
Heart-Based Hemangiosarcoma
This type
of tumor tends to exert its life-threatening effects by bleeding. The
heart is enclosed in a sac called the “pericardium”. When the
hemangiosarcoma bleeds, the blood fills up the pericardium so full that
the heart inside is under so much pressure, it has no room to fill with
blood it has to pump. On chest x-ray, the heart is “globiod” meaning
spherical. In fact the actual heart is normal shape but all that can be
seen is the round heart shadow of the pericardium filled with blood. An ultrasound is the only true way to see the effusion. If allowed to progress, this
condition results in an emergency circulating collapse called a “pericardial
tamponade” and is relieved by tapping the pericardium
using a needle to extract the excess fluid. 63% of heart-based
hemangiosarcomas have tumor spread at the time of discovery. Survival
time with surgery alone is
approximately 4 months.
Chemotherapy is recommended to create an improvement in survival time. |